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Yong-Qing Zhou Selected Research

N- (4- (2- amino- 3- chloropyridin- 4- yloxy)- 3- fluorophenyl)- 4- ethoxy- 1- (4- fluorophenyl)- 2- oxo- 1,2- dihydropyridine- 3- carboxamide

5/2014Prevention of BMS-777607-induced polyploidy/senescence by mTOR inhibitor AZD8055 sensitizes breast cancer cells to cytotoxic chemotherapeutics.
1/2014Synergistic activities of MET/RON inhibitor BMS-777607 and mTOR inhibitor AZD8055 to polyploid cells derived from pancreatic cancer and cancer stem cells.
5/2013Small-molecule inhibitor BMS-777607 induces breast cancer cell polyploidy with increased resistance to cytotoxic chemotherapy agents.

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Yong-Qing Zhou Research Topics

Disease

15Neoplasms (Cancer)
04/2016 - 09/2002
4Breast Neoplasms (Breast Cancer)
04/2016 - 05/2013
4Carcinogenesis
12/2014 - 06/2006
3Polyploidy
05/2014 - 05/2013
3Pancreatic Neoplasms (Pancreatic Cancer)
01/2014 - 05/2011
3Colonic Neoplasms (Colon Cancer)
07/2011 - 08/2010
2Parkinson Disease (Parkinson's Disease)
11/2021 - 03/2005
2Glioblastoma (Glioblastoma Multiforme)
11/2021 - 01/2014
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
06/2016 - 04/2016
1Colorectal Neoplasms (Colorectal Cancer)
12/2014
1Retinoblastoma (Glioblastoma, Retinal)
05/2014
1Glioma (Gliomas)
01/2014
1Leukemia
09/2013
1Hypoxia (Hypoxemia)
05/2011
1Lymphoproliferative Disorders (Lymphoproliferative Disorder)
10/2008
1Hemorrhagic Shock
11/2006
1Shock
11/2006
1Wounds and Injuries (Trauma)
11/2006
1Lung Injury
11/2006
1Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage)
05/2005
1Intracranial Vasospasm
05/2005
1Adenocarcinoma
01/2003
1Adenoma (Adenomas)
11/2002
1Adenocarcinoma of Lung
11/2002
1Inflammation (Inflammations)
02/2002

Drug/Important Bio-Agent (IBA)

15Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
04/2016 - 09/2002
6Monoclonal AntibodiesIBA
04/2016 - 06/2006
5Pharmaceutical PreparationsIBA
06/2016 - 05/2011
4Biological ProductsIBA
06/2016 - 09/2002
4Small Interfering RNA (siRNA)IBA
01/2014 - 06/2006
3N- (4- (2- amino- 3- chloropyridin- 4- yloxy)- 3- fluorophenyl)- 4- ethoxy- 1- (4- fluorophenyl)- 2- oxo- 1,2- dihydropyridine- 3- carboxamideIBA
05/2014 - 05/2013
3Tyrosine Kinase InhibitorsIBA
05/2014 - 05/2013
2(5- (2,4- bis((3S)- 3- methylmorpholin- 4- yl)pyrido(2,3- d)pyrimidin- 7- yl)- 2- methoxyphenyl)methanolIBA
05/2014 - 01/2014
2Aurora Kinase BIBA
01/2014 - 05/2013
2macrophage stimulating proteinIBA
07/2013 - 06/2010
2LigandsIBA
07/2013 - 06/2010
1Calcium Channels (Calcium Channel)IBA
11/2021
1CalcineurinIBA
11/2021
15-HT2A Serotonin Receptor (5 HT2A Receptor)IBA
11/2021
1pimavanserinIBA
11/2021
1Sulfides (Thioethers)IBA
04/2016
1Maytansine (Maitansine)IBA
12/2014
1DNA (Deoxyribonucleic Acid)IBA
05/2014
1A-Form DNA (A-DNA)IBA
05/2014
1GalactosidasesIBA
05/2014
1SurvivinIBA
05/2014
1sepantroniumIBA
05/2014
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
01/2014
1Epidermal Growth Factor (EGF)IBA
01/2014
1enhanced green fluorescent proteinIBA
01/2014
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2014
1Growth Factor ReceptorsIBA
01/2014
1Oncogene Proteins (Oncogene Protein)IBA
09/2013
15- ((2,6- dichlorobenzyl)sulfonyl)- 3- ((3,5- dimethyl- 4- ((2- (pyrrolidin- 1- ylmethyl)pyrrolidin- 1- yl)carbonyl)- 1H- pyrrol- 2- yl)methylene)- 1,3- dihydro- 2H- indol- 2- oneIBA
07/2013
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
07/2013
1Therapeutic UsesIBA
05/2013
1TubulinIBA
05/2013
1Fluorouracil (Carac)FDA LinkGeneric
07/2011
1Doxorubicin (Adriamycin)FDA LinkGeneric
05/2011
1AntibodiesIBA
08/2010
1Human Serum AlbuminFDA LinkGeneric
11/2006
1Ringer's LactateIBA
11/2006
1AlbuminsIBA
11/2006
1Peroxidase (Myeloperoxidase)IBA
11/2006
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
11/2006
1beta CateninIBA
07/2005
1NADPH Oxidases (NAD(P)H oxidase)IBA
05/2005
1acetovanillone (apocynin)IBA
05/2005
1Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA
03/2005
1NeurotoxinsIBA
03/2005
1RON proteinIBA
11/2002
1Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
02/2002

Therapy/Procedure

7Therapeutics
11/2021 - 07/2011
1Drug Therapy (Chemotherapy)
05/2013
1Liver Transplantation
10/2008
1Organ Transplantation
10/2008
1Laparotomy
11/2006
1Resuscitation
11/2006